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10/30/2015

Why Quitting Smoking Won't Eliminate Lung Cancer Deaths

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by Lynne Eldridge MD. Originally posted on 30 October 2015 at About.com.


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Many of us have been upset recently as well-meaning organizations have made smoking cessation the focus of lung cancer awareness month.  Certainly, encouraging the public to never begin, and to quit if they smoke, is admirable. And for people with lung cancer, quitting may improve survival.  Yet lung cancer awareness month should have a different focus.

Spreading information on smoking cessation does little overall for those living with lung cancer today. Five months after receiving a diagnosis of lung cancer, only 14% of people with the disease are smokers.  To focus on smoking is analogous to making breast cancer awareness month all about informing women that they should have their first child before the age of 30 (to decrease the risk of breast cancer.) Awareness month should be about supporting people with the disease, not about discussing the causes.

Awareness month should also be about funding to research better treatments. Those who smoked in the past won't benefit from a lecture about what they may have done differently 20 years ago.  Instead, they need treatment today. And for never smokers with the disease--not uncommon considering lung cancer in never smokers is the 6th leading cause of cancer deaths in the U.S.--this focus makes a month designed to celebrate their lives irrelevant. 

Some people may remain skeptical, but read on for further reasons why lung cancer awareness month should not have smoking cessation as the central focus.

The majority of people with lung cancer are non-smokers.

This heading is not a typo.  The majority—roughly 60% of people—diagnosed  with lung cancer are non-smokers.  This includes people who smoked at some time in the past, as well as never smokers.  In the United States 20% of women with lung cancer are never smokers, with that number rising to 50% of women with lung cancer worldwide.

Numbers such as 20% may seem small, until you take a look at the statistics.

Lung cancer is the leading cause of cancer deaths in both men and women in the United States.  Lung cancer kills twice as many women as breast cancer, and 3 times as many men as prostate cancer.  

And while around 30 to 40% of people smoke at the time of diagnosis, only 14% of people with lung cancer are smoking 5 months after diagnosis.

In other words, the vast majority of people with lung cancer today will not benefit from hearing about the hazards of smoking.  Not only is this focus not helpful, but it serves to propagate the stigma of lung cancer as a smoker's disease.  Unfortunately this vast majority, including most never smokers, have already been subjected to the blame game.  Have breast cancer?  Nice.  People act loving and ask how they can help you.  Have lung cancer?  Raised eyebrows accompanied by some variation of the question,"How long did you smoke?"  
There are many reasons that living with lung cancer can be harder than living with breast cancer.  Let's not add cancer awareness month to the list.

There are Other Causes of Lung Cancer

There are many causes of lung cancer. Even if tobacco had never been introduced on the planet, we would still have lung cancer.  Yes, smoking is the leading cause of lung cancer, but causes other than smoking are very important.  Though the number seems small—20%  of women who develop lung cancer being never smokers—this translates to a fifth of the 71,660 lung cancer deaths in women expected for 2015.

Radon exposure in the home is the second leading cause of lung cancer, and the number one cause of lung cancer in non-smokers.

Roughly 21,000 people die from radon-induced lung cancer each year, and this cause is entirely preventable.  Picking up a radon test kit from the hardware store for around 10 bucks, and having radon mitigation done if the test is abnormal, is all that's needed.

Putting these numbers in perspective may help.  Around 39,000 women are expected to die from breast cancer in 2015.  If we had a $10 test to check for a risk factor, and a procedure costing less than a grand that could completely prevent half of breast cancer deaths, do you think we would have heard?  Why doesn't the public know about this?  It goes back to the focus of this article; we are placing the emphasis of lung cancer awareness on smoking, and in doing so, are leaving the public with a false sense of assurance that all's well if you don't smoke.

There are other causes worth mentioning, from air pollution, to indoor air pollution, to secondhand smoke, to occupational hazards.  Don't assume you are safe if you never smoked.


Learn about the other causes of lung cancer in non-smokers and what you can do to reduce your risk.

People Who Have Quit Smoking Are Still at Risk

Quitting smoking certainly reduces the risk of lung cancer, but for most, some risk always remains.  The numbers in the last slide attest to this.  There are more former smokers who develop lung cancer each year than current smokers.

If you smoked in the past, don't fret yet.  After 10 years of quitting, the risk of lung cancer decreases by 30 to 50%. There are also some ways of reducing your risk of dying from lung cancer.

One method is low dose CT lung cancer screening.  While screening doesn't lower the chance that you will get lung cancer, it does increase the chance that if you develop lung cancer, it will be found in the earlier, more curable stages of the disease.  It's thought that screening people at risk could reduce the mortality rate from lung cancer by 20% in the United States.  Screening is currently recommended for people between the ages of 55 and 80, who have a 30 pack-year history of smoking, and continue to smoke or quit within the past 15 years.  In some cases screening may be recommended for other people based on personal risk factors for lung cancer.

In addition, studies looking at exercise and lung cancer as well as diet and lung cancer suggest there are some things that both people without and people with lung cancer can do to lessen risks. 

The Stigma Interferes With Early Diagnosis

My favorite part of lung cancer events I attend, is when lung cancer survivors share their story.  A special time, but oh so painful.  Time and time again people share what eventually led to their diagnosis -- often a series of visits, with several doctors, over a period of months, during which time they have been diagnosed with everything from asthma to Lyme disease.

Lung cancer flies below the radar screen for many health care professionals, especially lung cancer in never smokers and lung cancer in young adults.

For this reason, many are diagnosed when lung cancer has already spread, and the chance of a cure with surgery has passed.  In fact, young adults and never smokers are more likely to be diagnosed at an advanced stage of the disease.
Until we have a widespread screening tool for lung cancer, it's important for health professionals and patients alike, to realize that all you need to get lung cancer is lungs.  The symptoms of lung cancer can be different in non-smokers than smokers, and those of lung cancer in women are often different than symptoms in men.  Be your own advocate.  If you have any symptoms that aren't adequately explained, ask for a better explanation or a second opinion.  If we are to find lung cancer early, we need to dispel the myth that lung cancer is a smoker's disease.  That's part of what lung cancer awareness month is all about.

The Stigma Interferes With Research for New Treatments

Private funding for breast cancer surpasses that of lung cancer by a great distance, as evidenced by Susan G. Komen being a household word and pink ribbons having a widely recognized significance.  How many people can name the largest non-profits for lung cancer, and how many people even know the color of the lung cancer ribbon?

Public funding also lags far behind for lung cancer, and this is important because funding means dollars which in turn means research.

In 2012, federal research spending added up to $26,398 per life lost to breast cancer, vs only $1,442 per life lost from lung cancer.  I have often wondered what the survival rate for lung cancer would be if the same amount of money and research had been invested as has been with breast cancer.

Why is the funding so low, and why are researchers less likely to devote themselves to lung cancer?  The stigma.  There is an unseen, unheard statement that says, "These people smoked so they deserve to have cancer."  Nobody deserves to have lung cancer, whether a never smoker or a lifelong smoker. Making smoking cessation the focus of lung cancer awareness only increases this stigma and gap. 

The Stigma Interferes With Research About Causes

I made a comparison earlier about deaths from breast cancer, vs that from radon-induced lung cancer. That can be taken a step further.  I read studies galore looking at possible causes of breast cancer, as well as dietary and other measures which may reduce the risk. It's rare when I find similar studies looking at lung cancer.  

What is causing lung cancer in non-smokers?  Why is lung cancer increasing in young, never smoking women?

We need to change the face of lung cancer, so that we can begin to look at possible answers to these questions.

Lung Cancer is Increasing in Young, Never-Smoking Women

Most of us have read the headlines in recent years.  Lung cancer in men is now decreasing in the United States, while that in women has leveled off.  Yet there is one group for whom lung cancer is steadily increasing.  Young, never-smoking women.

These women have to put up with constant questions about their smoking status, or another variant, "Did your parents smoke when you were growing up?" 
Why can't we treat these women as we treat women with breast cancer in October?

Lung cancer isn't a "smoker's disease."  Someone with lung cancer could be your mother or your daughter or your sister or your aunt. These young women deserve to know that they aren't being dismissed for having a smoker's disease, while at the same time coping with the stigma.

Focus of Lung Cancer Awareness Month

Okay.  So smoking cessation shouldn't be the focus of lung cancer awareness month.  What should be at the center of awareness?

Number one should be support.  Every single person with lung cancer -- regardless of smoking history -- deserves our love, compassion, and the best care possible. Think of how women are treated during breast cancer awareness month, how they are celebrated, how they are reminded that research is being done to make a difference.

If you just don't know what to say, check out these tips on things not to say to someone with lung cancer.  How would you treat your friend or loved one with lung cancer differently, if she had breast cancer instead?

Number two should be about awareness.  Not smoking cessation as this is done everywhere year round.  Instead awareness that lung cancer occurs in non-smokers and having knowledge of the early symptoms could make a difference. Those who are former smokers should have the opportunity to learn about screening options.

And just as breast cancer awareness month raises funds for research, lung cancer awareness month should also be a time to educate and encourage those with lung cancer about new advances, while providing funding for further advances.

A Word About Smoking and Lung Cancer

For smokers with lung cancer, quitting is critical. To speak of separating lung cancer awareness month from smoking is not to dismiss smoking as a cause of lung cancer.  It is.  

For the minority of people living with lung cancer who smoke, quitting is incredibly important, and likely the most important thing anyone can do to improve survival.  Check out these 10 reasons to quit smoking after a diagnosis of cancer. Quitting smoking after a diagnosis of lung cancer improves the response to cancer treatments, improves quality of life, and improves survival.

For those without lung cancer, quitting not only reduces lung cancer risk, but improves survival in other ways. In addition to lung cancer, there are many cancers that are associated with smoking, and many other medical conditions associated with smoking.

The Quit Smoking Toolbox is a free resource to help you gather the tools you need to be successful in giving up the habit.

But remember that these tips on smoking and cancer were placed at the end for a reason.  They apply to only a minority of people living with lung cancer today.


Sources:
Amato, D. et al. Tobacco Cessation May Improve Lung Cancer Patient Survival. Journal of Thoracic Oncology. 2015. 10(7):1014-9.
American Cancer Society. Cancer Facts & Figures 2015. Accessed 06/08/15. http://www.cancer.org/acs/groups/content/@editorial/documents/document/acspc-044552.pdf
American Society of Clinical Oncology. Cancer.net Tobacco Use During Cancer Treatment. 04/2012. http://www.cancer.net/navigating-cancer-care/prevention-and-healthy-living/tobacco-use/tobacco-use-during-cancer-treatment
Amato, D. et al. Tobacco Cessation May Improve Lung Cancer Patient Survival. Journal of Thoracic Oncology. 2015. 10(7):1014-9.
Howlader, N., Noone, A., Krapcho, M., Garshell, J., Miller, D., Altekruse, S., Kosary, C., Yu, M., Ruhl, J., Tatalovich, Z., Mariotto, A., Lewis, D., Chen, H., Feuer, E., and A. Cronin (eds). SEER Cancer Statistics Review, 1975-2012, National Cancer Institute. Bethesda, MD, based on November 2014 SEER data submission, posted to the SEER web site, April 2015. http://seer.cancer.gov/csr/1975_2012/
National Cancer Institute. Cancer Statistics. Accessed 06/08/15. http://www.cancer.gov/about-cancer/what-is-cancer/statistics
National Cancer Institute. Lung Cancer Prevention (PDQ). Updated 05/12/15. http://www.cancer.gov/types/lung/patient/lung-prevention-pdq#section/_12
National Cancer Institute. Smoking in Cancer Care—for Health Care Professionals. Accessed 08/01/15. http://www.cancer.gov/about-cancer/causes-prevention/risk/tobacco/smoking-cessation-hp-pdq#section/_1
Parsons, A. et al. Influence of smoking cessation after diagnosis of early-stage lung cancer on prognosis: systematic review of observational studies with meta-analysis. British Medical Journal BMJ2010:340:b5569. Published online 21 January 2010.

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9/10/2015

Results from Genomics of Young Lung Cancer Study Promises New Research, Better Outcomes & More Hope for Lung Cancer Patients

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SAN CARLOS, Calif.--(BUSINESS WIRE)--The Addario Lung Cancer Medical Institute (ALCMI) released preliminary results from its Genomics of Young Lung Cancer Study (GoYLC) at the World Conference on Lung Cancer on September 8. These findings showed that more than 75 percent of trial participants have a driver mutation treatable with targeted therapies or precision medicine.

“These findings provide the foundation for improved outcomes for lung cancer patients by driving genomic testing, precision medicine and targeted treatment”

The study, launched in July 2014, aims to understand why lung cancer occurs in young adults who are quite often athletic, and never smokers. Last year alone an estimated 4,500 people under 45 were diagnosed with lung cancer.

ALCMI, a patient-centric, international research consortium and partner of the Bonnie J. Addario Lung Cancer Foundation (ALCF) facilitated this first-of-its-kind, multi-institutional, prospective genomic study to characterize a new genome-defined subtype of lung cancer and accelerate delivery of more effective targeted therapies.

To participate in the GoYLC study, patients must have pathologically confirmed primary bronchogenic lung carcinoma at any stage and any treatment point and be under the age of 40 at the time of diagnosis.

“These findings provide the foundation for improved outcomes for lung cancer patients by driving genomic testing, precision medicine and targeted treatment,” said Bonnie J. Addario, Stage IIIB lung cancer survivor and founder of both ALCF and ALCMI. “From the moment we saw our first 22-year-old lung cancer patient five years ago we began to hear from many young adults worldwide with lung cancer and became determined to identify and address an unmet need that could benefit all lung cancer patients.”

“Those diagnosed with lung cancer under the age of 40 tend to be never smokers and have Stage IV Adenocarcinoma at presentation,” said Barbara Gitlitz, MD, medical oncologist at the Keck School of Medicine of the University of Southern California (USC) and lead researcher for the GoYLC study. “We originally hypothesized that young adults with lung cancer might be an enriched population for targetable mutations; thus far we have far exceeded our statistical expectations. Our study is also quite novel allowing for web based participation so anyone in the world can join and use social media to share our trial information. Our initial findings provide a tremendous opportunity to drive innovative research and more impactful treatment for young lung cancer patients.”

Patients enrolled thus far in the GoYLC study are located in the United States, Europe and Australia. ALCMI’s approach allows for a feasible, seamless way to conduct research across continents.

“We are honored to provide the opportunity for lung cancer patients to help drive research and build their own treatment options for the future, and to work collaboratively with the leading lung cancer researchers and academic and community medical centers globally to help develop and accelerate new and improved diagnostics and therapies, ” said Steven Young, president and COO of ALCMI.

For more information about the study, please contact Steven Young at 203-226-5765 or [email protected]. Lung cancer patients may learn more at https://www.openmed.org/site/alcmi-goyl.

For more information about the ALCF please visit www.lungcancerfoundation.org or follow us on Facebook or Twitter.

About the Bonnie J. Addario Lung Cancer Foundation
The Bonnie J. Addario Lung Cancer Foundation (ALCF) is one of the largest philanthropies (patient-founded, patient-focused, and patient-driven) devoted exclusively to eradicating Lung Cancer through research, early detection, education, and treatment. The Foundation’s goal is to work with a diverse group of physicians, organizations, industry partners, individuals, patients, survivors, and their families to identify solutions and make timely and meaningful change and turn lung cancer into a chronically managed disease by 2023. The ALCF was established on March 1, 2006 as a 501c(3) non-profit organization and has raised nearly $25 million for lung cancer research and related programs.

About the Addario Lung Cancer Medical Institute
The Addario Lung Cancer Medical Institute (ALCMI), founded in 2008 as a 501c(3) non-profit organization, is a patient-centric, international research consortium driving research otherwise not possible, evidenced by ALCMI's current clinical studies CASTLE, INHERIT EGFR T790M, and the Genomics of Young Lung Cancer. ALCMI overcomes barriers to collaboration via a world-class team of investigators from 22+ institutions in the U.S. and Europe, supported by dedicated research infrastructures such as centralized tissue banks and data systems. ALCMI directly facilitates research by combining scientific expertise found at leading academic institutions with patient access through our network of community cancer centers – accelerating novel research advancements to lung cancer patients.

Contacts
Perry Communications Group
Julia Spiess Lewis, 916-658-0144
[email protected]

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8/31/2015

A Must-Read:  "Lung Cancer - Why You Should Care"

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Bonnie Addario, lung cancer survivor and founder of the Bonnie J. Addario Lung Cancer Foundation and the Addario Lung Cancer Medical Institute, pens a powerful piece for the Huffington Post today. 

Read it HERE and share it today!
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8/31/2015

TUNE IN TO "START-UP U" ON TUESDAY, SEPTEMBER 1ST! STARTUP LEGEND AND PREMIERE VENTURE CAPITALIST TIM DRAPER GENEROUSLY PLEDGES ONE MILLION DOLLARS TO CHARITY - INCLUDING THE ADDARIO LUNG CANCER FOUNDATION!!!

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Draper Will Donate the Money When Tuesday’s All-New Episode of “Start-Up U” Hits One Million Viewers

Burbank, CA (August 18, 2015) – Start up legend Tim Draper will donate one million dollars to charity if as many viewers watch ABC Family’s unscripted series “Startup U” on Tuesday, September 1 at 10:01PM ET/PT on ABC Family.
 
On Saturday, Tim Draper announced via Twitter and Facebook that he will donate one million dollars to charity if one million viewers tune-in to Tuesday’s all-new episode. Not only does Draper have a long history of donating to worthy causes close to his heart, but he is a champion of entrepreneurism; his life’s mission is to create a better future for everyone. “I believe in the series and the great work these kids are doing. What better way to support them than connecting it back to a worthy cause? This is a win/win situation for everyone, but especially the charities.”
 
Charities that will benefit from Draper’s benevolence are ones very close to his heart, including the Parkinson’s Institute (in honor of his mother, who fights this disease), Bizworld, Tourettes Association of America (his brother-in-law and nephews are affected), Smith College Women’s business plan competition, Endeavor (supports third world entrepreneurship), Defy (works with former prisoners when they have paid their debt to society, Cal Arts and California State Summer School for the Arts, and the Addario Lung Cancer Foundation (amember of his staff is a survivor).
 
Viewership will be measured by all methods, including mobile and online viewing, L+3 and L+7.
 
In Tuesday’s episode, titled “Bro’s & Bras,” it’s Evangelism Week, which teaches the students how to become experts at selling their brand. Tim putseveryone in yet another challenging situation when he sends them to San Francisco to sell men and women’s underwear to the many shoppers in Union Square. There’s a catch, though: they have to sell the undergarments based on only a picture, with no actual product. Frustrated by the process, Tony makes a decision that irritates Sequoia and his classmates. Sharon meets with resistance when she pitches Hotpoint to various venues around the Bay Area, only to have things get tougher when Tim puts her in the hot seat. Meanwhile, Michael Volpatt (Partner, Larkin/Volpatt Communications) and Charlie meet with several students to evaluate their brands.
 
“Startup U” is produced by Ugly Brother Studios, a Sky Vision partner. Mike Duffy, Tim Duffy, Tim Draper, Perry Dance and Ted Iredell serve as executive producers.
 
Part of the Disney|ABC Television Group, ABC Family is distributed in 94 millionhomes. ABC Family entertains and connects to audiences with bold, relatableprogramming that celebrates the epic adventure of becoming an adult, from first kiss to first kid. ABC Family's programming is a combination of network-defining original series and original movies, quality acquired series and blockbuster theatricals. “WATCH ABC Family” is an authenticated service which allows viewers with participating TV subscription services access to 24/7 live viewing of the network, as well as continued on-demand access to such popular series at home and on-the-go via a wide array of devices. ABC Family is also the destination for annual holiday events with "13 Nights of Halloween" and "25 Days of Christmas."
 
ABC Family Media Relations: Joelle Johnson, (818) 569-7746, [email protected]
 
For additional press materials, please visit http://www.disneyabcpress.com/abcfamily/
 
Facebook: www.facebook.com/StartUpUTV

Twitter: twitter.com/StartUpUTV

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8/19/2015

What Non-Smokers Need to Know About Lung Cancer

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Why are so many women who have never lit up
developing this disease?

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Photo: Javier Pérez
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By Aimee Swartz
(This article was originally published in the September 2015 issue of O, The Oprah Magazine.)

In 2012, Sandy Jauregui-Baza was hiking along the Tamul waterfall in San
Luis Potosí, Mexico, when she started coughing and having trouble breathing. 
"I remember thinking I must be coming down with something," she recalls. 

Jauregui-Baza was an avid exerciser; she ran or hiked daily, logging more than 100 miles each month. She ate clean, avoiding almost all processed foods. She figured she was too healthy for anything to be seriously wrong. But after developing flu-like symptoms, she went to an urgent care clinic in Los Angeles. The doctor thought it might be tuberculosis, based on the results of her cloudy chest X-ray and her recent honeymoon in Nepal, where the infectious disease is common. But a few days later, when the definitive test for TB came back negative, doctors did a lung biopsy to look for other causes. 

The final diagnosis: Jauregui-Baza had stage IV lung cancer, the most advanced form of the disease; it had spread into the bones of her spinal column. "I thought the doctors had to be kidding," says Jauregui-Baza, now 32. "I've never even smoked, and I had just hiked to the base camp of Mount Everest. How could I have lung cancer?" The prognosis was grim: More than 95 percent of stage IV lung cancer patients succumb to the disease within five years of diagnosis. Jauregui-Baza was given just six months to live. 

Until about a decade ago, most doctors considered it nearly impossible for young nonsmokers to develop lung cancer. "It would have been assumed that a tumor found on the lung had spread from cancer elsewhere in the body," says David Carbone, MD, PhD, director of the James Thoracic Center at the Ohio State University Comprehensive Cancer Center. Today doctors know that isn't always the case: About one in five of the estimated 105,590 American women who will be diagnosed with the disease this year are what doctors call "never-smokers"—those who have literally never lit up or who have smoked fewer than 100 cigarettes in their lifetime. A 2012 French study revealed that from 2000 to 2010, rates of lung cancer among never-smokers shot up an alarming 33 percent. In fact, if lung cancer in nonsmokers was its own category, it would rank among the ten deadliest cancers in the United States. This is in part because the symptoms—coughing, chest pain, shortness of breath—are so similar to those of common illnesses; as a result, the disease is often ignored by patients and overlooked by physicians. 

That's what happened to Natalie DiMarco, a nonsmoker who was diagnosed at age 32. During a personal-training session one day, she was so winded, "it stopped me in my tracks," she says. "It didn't seem like I was just tired from exercise." She made an appointment to see her primary care physician, who thought allergies were to blame. When she developed a nagging cough, she sought another opinion and was diagnosed with pneumonia. By the time her cancer was discovered through a biopsy six months later, DiMarco could no longer climb a flight of stairs without stopping to catch her breath. Like Jauregui-Baza, she had stage IV lung cancer. 

If cigarettes aren't to blame, what is? Certainly, secondhand smoke plays a role, as do other environmental factors: According to the U.S. Environmental Protection Agency, a leading cause of lung cancer in nonsmokers is exposure to radon, a radioactive gas, and in 2013, the World Health Organization officially recognized outdoor air pollution as another cause. But experts believe these factors account for only a fraction of lung cancer cases among young never-smokers. "These patients just aren't old enough to have had the degree of exposure we would typically associate with cancer," says Pasi A. Jänne, MD, PhD, director of the Lowe Center for Thoracic Oncology at Dana-Farber Cancer Institute in Boston. Though studies have linked lung cancer in never-smokers to other factors, from estrogen to viral infections like HPV, none has emerged as a definitive cause. 

Researchers are having success looking for answers in the very place where cancer begins—our DNA. Advances in gene-sequencing technologies have helped doctors discover that certain cancer-causing mutations occur about two to six times more often in tumors of never-smokers than in tumors of those who have a history of lighting up. The good news: The FDA has approved drugs that can home in on these mutations and deactivate them. Although the meds are not a cure, they can buy some patients more time—sometimes years—before the cancer returns; in one clinical trial, a drug called Xalkori was found to slow the progression of a type of lung cancer more than twice as long as chemo. 

Jauregui-Baza had been on Xalkori for more than two years and says it allowed her to live "almost the same life as before cancer." Recently, however, it stopped working. Now on a new drug, she's also taking part in a first-of-its-kind study by the Addario Lung Cancer Medical Institute that's looking specifically at the DNA of young people with lung cancer. The hope is to identify additional mutations that could point the way to better treatments. Jauregui-Baza remains optimistic: "If I can stay alive until the next treatment comes, I have a good shot at beating this."

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7/24/2015

The Bonnie J. Addario Lung Cancer Foundation Honors Leading Lung Cancer Researcher with the 2015 Addario Lectureship Award

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Fred R. Hirsch, MD, PhD, honored at the 16th International
Lung Cancer Congress

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SAN CARLOS, Calif., July 24, 2015 /PRNewswire-USNewswire/ -- The Bonnie J. Addario Lung Cancer Foundation (ALCF) will honor Fred R. Hirsch, M.D., Ph.D., with the 2015 Addario Lectureship Award for his continued leadership and expertise in lung cancer treatment and research. Dr. Hirsch, CEO of the International Association for the Study of Lung Cancer (ISLAC), will receive the award at the 16th International Lung Cancer Congress held on July 30 – August 1 in Huntington Beach, California.

"Dr. Hirsch's contribution and dedication to lung cancer research is truly remarkable," said Bonnie J. Addario, 10-year lung cancer survivor and founder of the ALCF. "Dr. Hirsch is a cancer survivor which makes him very sensitive to patients and increases his commitment to their survival. We are thrilled to present him with the eighth Addario Lectureship Award to highlight his commitment to eliminate lung cancer worldwide. "

Known best for his unsurpassed research on the diagnostic tool, fluorescent in situ hybridization (FISH), colleagues David Gandara M.D., Associate Director, Clinical Research at the UC Davis Cancer Center and Roy Herbst, Ensign Professor of Medicine and Chief of Medical Oncology at the Yale Cancer Center have nicknamed him the "Big Fisherman."

Dr. Hirsch has been a professor of medicine at the University of Colorado Cancer Center and professor of medicine and pathology at the University of Colorado, Denver since 1999. He also serves as the conference president for the World Conference on Lung Cancer. Dr. Hirsch received his MD and PhD from the University of Copenhagen, Denmark and served as chief physician at the department on oncology at the Finsen Center in Copenhagen from 1996 to 1999. He has been a supervisor for many European and Asian post-doctoral trainees in his lab at the University of Colorado Cancer Center.

"There is no one in the entire world that has been more dedicated to IASLC and addressing lung cancer worldwide," said Paul Bunn, Jr., MD, distinguished professor, division of medical oncology at the University of Colorado and James Dudley chair in lung cancer research. "Fred has a unique perspective – he is not only both a pathologist and a medical oncologist but also has trained and practiced in both Europe and the U.S. He has been involved in studies of lung cancer diagnosis, staging, prevention, early detection and treatment that have revolutionized the care of lung cancer patients. He works diligently to bridge international ties for lung cancer and recognizes it is a global disease that requires a global effort."  

Dr. Hirsch received the Mary J. Matthews Distinguished Scientific Award from ISLAC, the Japanese Lung Cancer Society Merit Award, the British Medical Association Medical Book Award, The Annals of Oncology Award, the Lise and Gunnar Waerums Foundation Award, the Fru Agnes Andressons Memory Award and the Lung Cancer Foundation of America Young Investigator Award, among many others. He has authored hundreds of peer-reviewed papers and has current funding for his work on Squamous Cell lung cancer from ISLAC.

"Dr. Hirsch is working diligently to bridge international ties for lung cancer, sparking a global effort to address a global disease," said Addario. "We are honored to recognize him as a scientist, a physician and a friend."

Past Addario Lectureship Award recipients include:
  • 2014 Recipient: Roy S. Herbst, M.D., Ph.D., Ensign Professor of Medicine and Chief of Medical Oncology, Yale Cancer Center
  • 2013 Recipient: Tony Mok, M.D., Professor in the Department of Clinical Oncology, Chinese University of Hong Kong in Prince of Wales Hospital in Hong Kong
  • 2012 Recipient: D. Ross Camidge, M.D., Ph.D., Director of the Thoracic Oncology Clinical Program and Associate Director for Clinical Research, Colorado University Cancer Center
  • 2011 Recipient: William Pao , M.D., Ph.D., Associate Professor of Medicine, Ingram Associate Professor of Cancer Research, Director, Personalized Cancer Medicine, Vanderbilt Ingram Cancer Center
  • 2010 Recipient: David R. Gandara , M.D., Associate Director, Clinical Research, UC Davis Cancer Center
  • 2009 Recipient: Harvey Pass , M.D., B.A., Director of the Division of Thoracic Surgery and Chief of Thoracic Surgery, New York University Medical Center
  • 2008 Recipient: Paul A. Bunn, Jr. M.D., Principal Investigator and Director, University of Colorado Cancer Center

The ALCF has supported the Lung Cancer Congress for the past eight years and serves as a co-sponsor along with the IASLC. The annual three-day event provides physicians with practical information about the clinical implications of lung cancer screening, the latest clinical data impacting the treatment of lung cancer and novel agents and strategies that are changing the future of lung cancer therapy.

About the Bonnie J. Addario Lung Cancer Foundation
The Bonnie J. Addario Lung Cancer Foundation (ALCF) is one of the largest international philanthropies (patient-founded, patient-focused and patient-driven) devoted exclusively to eradicating lung cancer through research, early detection, education and treatment. The Foundation's goal is to work with a diverse group of physicians, organizations, industry partners, individuals, patients, survivors and their families to identify solutions and make timely and meaningful change and turn lung cancer into a chronically managed disease by 2023. The ALCF was established on March 1, 2006, as a 501c(3) non-profit organization and has raised nearly $25 million for lung cancer research and related programs.

Photo - http://photos.prnewswire.com/prnh/20150724/242089 
Logo - http://photos.prnewswire.com/prnh/20140730/132466 
 
SOURCE Bonnie J. Addario Lung Cancer Foundation

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5/10/2015

Happy Mother's Day from The Joan Gaeta Lung Cancer Fund

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Happy Mother's Day to all the moms out there from the Gaetas!  To everyone else, we offer three simple words:  Love your mother.

We'd also like to take this opportunity to remind all the Georgia drivers out there that you can get your very own Lung Cancer Awareness Speciality License Plate today!  Click here for all you need to know!
Joan Marie Gaeta. Mother. 1938 - 2007.
Georgia Lung Cancer Awareness Specialty License Plate

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5/7/2015

IBM's Watson supercomputer to speed up cancer care.

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Originally published by the BBC on 6 May 2015.

IBM's supercomputer Watson will be used to make decisions about cancer care in 14 hospitals in the US and Canada, it has been announced.



Using computers to trawl through vast amounts of medical data speeds up the diagnosis process.

The system will help assess individual tumours and suggest which drug should be used to target them.

Doctors have welcomed the new computer which will learn from each case it examines.

"When you are dealing with cancer, it is always a race," said Dr Lukas Wartman, assistant director of cancer genomics at the McDonnell Genome Institute at Washington University in St. Louis, one of those signed up to use the Watson system.

"As a cancer patient myself, I know how important genomic information can be.

"Unfortunately, translating cancer-sequencing results into potential treatment options often takes weeks with a team of experts to study just one patient's tumour and provide results to guide treatment decisions. Watson appears to help dramatically reduce that timeline," he explained.

Pressing issue



Most people currently diagnosed with cancer will receive surgery, chemotherapy or radiation treatment.

But as genetic sequencing becomes increasingly accessible and affordable, some patients are starting to benefit from treatments that target their specific cancer-causing genetic mutations.

However the process is very time-consuming - a single patient's genome represents more than 100 gigabytes of data - and this needs to be combined with other medical records, journal studies and information about clinical trials.

What would take a clinician weeks to analyse can be completed by Watson in only a few minutes.

"The technology that we're applying to this challenge brings the power of cognitive computing to bear on one of the most urgent and pressing issues of our time - the fight against cancer - in a way that has never before been possible," explained Steve Harvey, vice president of IBM Watson Health.

According to Mr Harvey, Watson "will look for actionable targets", although he acknowledged that, "when institutions do genetic sequencing, only about half the cases come back with something actionable".

Sometimes it is impossible to identify the main mutation and, in other cases, no targeted therapy currently exists.

Those collaborating with IBM include the Cleveland Clinic, the Fred & Pamela Buffett Cancer Centre in Omaha and the Yale Cancer Centre.

Eleven others will join the programme by the end of 2015 and each will pay an undisclosed subscription fee to IBM.

Corporate medicine

The link-up is part of an increasingly close relationship between the medical community and technology corporations.

Apple revealed this week that it plans to develop apps for the iPhone that will allow users to take DNA tests which may reveal which diseases and health conditions they are likely to develop

It also recently teamed up with IBM to allow the software that helps gather health data from iPhones to be used by Watson.

IBM is convinced that Watson can "help change the face of healthcare" but it has even bigger ambitions for its cognitive computing platform.

Speaking at an IBM event this week, the firm's chief executive Ginni Rometty made a bold prediction for the technology, saying: "in the future, every decision mankind makes, every decision, is going to be informed by a cognitive system like Watson and, as a result, our lives in this world are going to be better for it."

Full Disclosure:  Joe Gaeta, President and CEO of The Joan Gaeta Lung Cancer Fund is also an employee of the IBM Corporation.

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4/14/2015

NavigateLungCancer.org:  A New Online Toolkit Now Available to Help People Living with Lung Cancer

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Originally published by Brandpoint (BPT) on Monday, April 13, 2015 12:00 am

A lung cancer diagnosis may bring up a variety of difficult emotions, and navigating the next steps involved in daily life can be especially overwhelming for patients and their loved ones. Emotions may range from anger at the loss of control and uncertainty about medical decisions to fear about what happens next. And these feelings may be coupled with the fact that when patients and their families go online to learn more, they see discouraging statistics on incidence or complex medical information, when what they really need is help dealing with the impact of lung cancer on their lives and emotions.

As hard as a lung cancer diagnosis can be, there is support and practical information available on NavigateLungCancer.org to help lung cancer patients and their loved ones during the days ahead. The website was designed to be a comprehensive, go-to resource supporting the lung cancer community holistically, providing practical, day-to-day information that goes beyond their diagnosis. In developing the site, Bristol-Myers Squibb partnered with seven leading patient advocacy organizations to ensure it would provide the type of logistical, financial and psychosocial resources that are needed and meaningful for the lung cancer community.

"NavigateLungCancer.org will allow patients and caregivers to spend more time focused on the path forward and less time figuring out the next step,” said Bonnie J. Addario, Founder and Chairman of the Bonnie J. Addario Lung Cancer Foundation. “A lung cancer diagnosis comes with a whole new set of day-to-day challenges and we've collaborated with other cancer organizations and stakeholders to collect nutritional, financial, organizational or even physical assistance services in one place and make it available for patients and their families.”

In addition, the site offers interactive resources that may help manage living with lung cancer and the impact on everyday activities, including the interactive “The Road Ahead” and “Personal Journal” tools.

The Road Ahead

Considered a simple guide for patients and their families to find the right resources at every juncture in their lung cancer journey, “The Road Ahead” includes an overview of organizations offering financial assistance for everyday activities, such as house cleaning, transportation services, fuel costs and meal delivery programs. Visitors can also find valuable information to address legal and financial concerns and community support groups.

A Personal Journal

Many faced with a lung cancer diagnosis need an outlet to articulate their emotions during a challenging and uncertain time. An online and downloadable “Personal Journal” tool allows patients and caregivers to record their hopes and fears via a series of questions developed by oncology social workers. Visitors who sign up to receive email updates from the website will also be mailed a treatment journal to keep track of appointments and capture thoughts and feelings.

Visitors to the site can also download educational assets and register to receive emails with helpful tips and supportive messages about what you or a loved one might be going through.

Beyond being a resource for patients and caregivers, the site is also optimized for nurses, providing educational videos that may allow them to learn more about lung cancer patient needs from patient advocacy groups and research in the field from clinical trial institutions.

NavigateLungCancer.org was developed by Bristol-Myers Squibb in partnership with the Cancer Research Institute, Lung Cancer Alliance, Bonnie J. Addario Lung Cancer Foundation, LUNGevity Foundation, Cancer Care, Cancer Support Community and Free to Breathe. Bristol-Myers Squibb does not endorse these organizations. The information provided is meant for informational purposes only and is not meant to replace a physician's medical advice.

Visit www.NavigateLungCancer.org for more information and updates on the latest lung cancer tools and resources.

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3/3/2015

Attention #Georgia Drivers!  Get your #LungCancer Awareness Specialty License Plates today!

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Georgia is the only state in the country to offer its drivers the option of  a lung cancer awareness specialty license plate.  Show your fellow motorists that, in Georgia, lung cancer matters!  

Check out LungCancerLicensePlate.org today!
Proceeds help The Joan Gaeta Lung Cancer Fund support important research!

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